Some state protocols allowed patients to choose between inhaled cannabis 62 and synthetic THC. In those studies which compared natural cannabis to dronabinol, inhaled cannabis was equal to or better than the oral administration of synthetic THC. Researchers in New Mexico observed similar findings. Researchers at the California Board of Pharmacy found that inhaled cannabis and oral THC produced similar results in patients.
However, physicians still rated natural cannabis as slightly more effective than oral THC as an anti-emetic. Today, several patient populations continue to use natural cannabis and its cannabinoids in large numbers despite its illegality and the availability of Marinol.
Cannabis use is also prevalent among patients with neurologic disorders. A British survey of MS patients found that 43 percent of respondents used natural cannabis therapeutically, with about half admitting they used it regularly.
A more recent Canadian survey published in Neurology reported that 14 percent of MS 76 patients and 21 percent of respondents with epilepsy had used medical cannabis in the past year.
Oral synthetic THC, legally available by prescription as Marinol, often provides only limited relief to a select group of patients, particularly when compared to natural cannabis and its cannabinoids.
Patients often experience minimal relief from Marinol and many experience unwanted side effects. In addition, many physicians are hesitant to prescribe the drug, and some patients are unable to afford it. The active ingredient in Marinol is a synthetic analogue of only one of the compounds in cannabis that is therapeutically beneficial to patients.
By prohibiting the possession and use of natural cannabis and its cannabinoids, patients are unnecessarily burdened to use a synthetic substitute that lacks much of the therapeutic efficacy of natural cannabis and its cannabinoids. Marinol should remain a legal option for patients and physicians and the development of additional cannabis-based pharmaceuticals should be encouraged.
Marinol Lacks Several of the Therapeutic Compounds Available in Natural Cannabis Chemical compounds in cannabis, known as cannabinoids, are responsible for its numerous therapeutic benefits. Share this: Twitter Facebook. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law. To stimulate appetite in people with AIDS, dronabinol is usually taken 1 hour before lunch and 1 hour before dinner.
Older adults may need to take this medicine less often. Follow your doctor's dosing instructions very carefully. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device not a kitchen spoon. You may need to follow a special diet while using dronabinol.
Follow all instructions of your doctor or dietitian. Learn about the foods you should eat to help boost your food intake. Do not stop using dronabinol suddenly after long-term use , or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine. Store the capsules or unopened liquid medicine in a tightly-closed container in the refrigerator. Do not freeze. You may also store the capsules at cool room temperature, away from moisture and heat.
After opening the liquid medicine, store it at room temperature. Throw away any unused liquid 42 days after opening the bottle. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.
Do not take two doses at one time. Overdose symptoms may include changes in mood, memory problems, little or no urinating, constipation, loss of energy, problems with speech or coordination, or feeling light-headed. Health Topics. Health Tools. Marinol Dronabinol. Generic Name: Dronabinol. If you have to take a drug screen for employment or other reasons, be sure to disclose you are taking a prescription for Marinol so this can be taken into account.
Learn the best ways to manage stress and negativity in your life. Marinol dronabinol. Highlights of prescribing information. Revised August Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics. Cancer Manag Res. National Highway Traffic Safety Administration. Marijuana-impaired driving: a report to Congress.
Published July An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions. J Addict Med. Your Privacy Rights. To change or withdraw your consent choices for VerywellMind. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page. These choices will be signaled globally to our partners and will not affect browsing data.
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